午夜福利1000集合

Fruit to suit

WALNUTS grown from genetically modified plants could soon be hitting the
supermarket shelves. The GM roots will beat off costly bacterial infections but
the nuts themselves will be GM-free. The hybrid plants, the first of their kind,
should appease both farmers and consumers wary of GM food.

Fruit tree and vine growers are plagued by Agrobacterium, a bug
which causes cancerous growths called galls in the roots. The bug gets into the
roots via a wound and transfers tumour-causing genes, which invade the plant鈥檚
DNA and the gall starts to form. Now Abhaya Dandekar and a team at the
University of California, Davis, say they can prevent the tumour genes being
expressed by triggering a plant defence mechanism.

They鈥檝e made GM varieties of thale cress and tomato that have versions of the
tumour-causing genes in their DNA. When expressed as mRNA, an intermediate stage
between a gene and a protein, the molecule鈥檚 structure forces it to fold back on
itself. Because plant cells don鈥檛 normally have double-stranded mRNA, they
鈥渟ilence鈥 the genetic material by chopping it up. This prompts the plant cells
to recognise the similar tumour gene mRNA as alien and chop it up.

A standard cultivation technique could be used to ensure that walnut trees
modified in the same way won鈥檛 produce GM fruit. Usually, the chosen fruiting
variety is grafted onto a root stock that copes well with local conditions. In
this case, non-GM plants would be grafted onto modified roots without the two
sets of genes mixing.

  • More at:
    Proceedings of the National Academy of Sciences (vol 98, p13,437)

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