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Shakespeare: The godfather of modern medicine

Epilepsy, psychiatric breakdown, sleep disorders – for all the crudity of 16th-century healthcare, Shakespeare's observations still inspire doctors today
Shakespeare: The godfather of modern medicine

(Image: Angus Greig)

Epilepsy, psychiatric breakdown, sleep disorders – for all the crudity of 16th-century healthcare, Shakespeare’s observations still inspire doctors today

EPILEPSY, psychiatric breakdown, sleep disorders… For all the crudity of 16th-century healthcare, there’s a surprising amount of modern medical detail in Shakespeare’s plays. The behaviours of some of his characters often bear a striking resemblance to how today’s doctors describe a range of neurological disorders, and his observations continue to inspire centuries after his death.

One of those inspired was . “The poets and philosophers before me discovered the unconscious,” Freud once said, which the literary critic Harold Bloom of Yale University thinks refers to Shakespeare. Indeed, Bloom contends that what we think of as the Freudian map of the mind is in fact Shakespeare’s.

Freud’s interest in Shakespeare may have crystallised while he attended lectures by another medical pioneer, Jean-Martin Charcot. Charcot is known as the father of neurology, and his theories on neurosis and hysteria led . He often used Shakespeare to illustrate the detailed observations of behaviour and character traits that are needed for diagnosis.

That’s a lesson many neurologists still appreciate. “The art of medicine is strikingly similar to storytelling,” says neurologist Brandy Matthews at the Indiana University School of Medicine in Indianapolis. “No matter how amazing the technology that supports clinicians, nothing trumps a careful history and physical examination.”

Following in Charcot’s footsteps, some neurologists, including Matthews, still use Shakespeare in their classes. They have also . It might be easy to mistake creative licence for medical observation, but the rich detail of the descriptions suggest that some of the symptoms might have been inspired by real-life encounters. – then a notorious mental institution best known by its nickname, Bedlam.

Of course, no one is saying that his dramas should be read as medical reports, but these observations may have helped bring his characters so vividly to life.

Bloom has gone as far as to say that Shakespeare “invented” the human. By this he means that while all the various character traits that are in Shakespeare existed before, few before Shakespeare had written them down in such detail, inspiring later generations to be more reflective when considering their own behaviours. Whether you agree with Bloom or not, Shakespeare’s influence on the medical understanding of the mind seems undeniable. Read on for the case notes of his most famous characters.

1. Name: The Macbeths

Description: Privileged, married, middle-aged Scottish couple

Supporting quotes: His: “Then comes my fit again.” Hers: “Out, damned spot! Out, I say!”

Macbeth reports hallucinations including a dagger floating in front of him and voices telling that he would sleep no more. As well as these symptoms he has impaired cognitive function, involuntary movements, insomnia and psychiatric breakdown. He had been in contact with a cauldron containing a possible source of infectious misshapen proteins known as prions, which would support a diagnosis of variant Creutzfeldt-Jakob disease (Clinical Infectious Diseases, vol 42, p 299).

Lady Macbeth is a different matter. She is able to get up and write a letter “all this while in the most fast asleep”. This is classic parasomnia, a condition whereby behaviours can be exhibited while asleep. She also has a form of obsessive-compulsive disorder, washing her hands for up to 15 minutes at a time in an attempt to remove an imagined stain: “What, will these hands ne’er be clean?” Handwashing is known to ease emotional stress.

2. Name: King Lear

Description: Elderly statesman and father

Supporting quote: “Where am I? …I am a very foolish, fond old man.”

King Lear, at over 80 years old, has lived far beyond the average life expectancy. His , a sign of Parkinson’s disease. He veers from psychosis, in which he doesn’t know his own daughter (“you are a spirit”), to moments of clarity when he recognises her (“I think this lady to be my child Cordelia”). The king even appears to believe himself dead (“You do wrong to take me out o’ the grave”) – an assertion seen in a disorder known as Cotard’s syndrome. Taken as a whole, his , a form of dementia associated with Parkinson’s.

“You do me wrong to take me out o’ the grave”

“Lear’s fluctuating lucidity, poor decision-making and suspiciousness could all make sense in the light of that diagnosis,” says Adam Zeman, a cognitive neurologist at the University of Exeter in the UK.

3. Name: Sir John Falstaff

Description: Alcoholic, overweight old man

Supporting quote: “If sack and sugar be a fault, God help the wicked.”

He may be sweet and kind, but Falstaff is also plump, addicted to sack (sherry) and suffers nightly from a treatable sleep disorder. The evidence comes from a report of Peto, a companion of Falstaff, who was asked to fetch him. “Falstaff!” he scoffed, “Fast asleep behind the arras, and snorting like a horse.” Prince Hal replied, “Hark, how hard he fetches breath.”

In people who are overweight, there may be constriction on the airways, and this narrowing can lead to sleep apnoea, the commonest form of sleep-disorder breathing. Falstaff may be a comic character, but sleep apnoea is not a trivial condition: .

4. Name: Othello

Description: High-ranking military man of African descent

Supporting quote: Desdemona says to Othello: “And yet I fear you; for you’re fatal then when your eyes roll so.”

Othello is a brave, honourable soldier, a man of free and open nature. But he is also a man prone to seizures that are associated with violence. Some transformation. “My lord is fallen into an epilepsy,” says Iago. “The lethargy must have its quiet course, if not he foams at the mouth, and by and by breaks out to savage madness.” Othello’s tragedy is complete when, during a seizure, he strangles his wife to death.

Evidence for a link between epilepsy and violence undertaken during seizures has been debated for centuries. A review of court cases from 1880 to 2013 found 178 occasions when epilepsy was used as a defence for murder. “” (Neuropsychiatric Disease and Treatment, vol 9, p 667).

Shakespeare: The godfather of modern medicine

David Tennant as Hamlet in 2008 (Image: Robbie Jack/Corbis)

5. Name: Hamlet

Description: Danish prince, aimless graduate

Supporting quote: “Man delights not me – no, nor woman neither.”

Recently bereaved Hamlet, a graduate around 30 years old, thinks life isn’t worth living, saying “I do not set my life at a pin’s fee”. He is melancholic and impulsive, accidentally killing his girlfriend’s father. Most of all he swings between moods superbly high and desperately low. He can be tender to his girlfriend, Ophelia, but then cruel (“Get thee to a nunnery: why wouldst thou be a breeder of sinners?”) and almost violent. His wit and insight is second to none but can manifest in extreme talkativeness and an inability to assess danger. He is also indecisive.

Under the latest edition of the Diagnostic and Statistical Manual of Mental Disorders, – an assessment that makes sense to Farah Karim-Cooper, a scholar at Shakespeare’s Globe theatre in London. “You can see evidence of his mood swings and rage in his chamber with his mother, and in his exchanges with Ophelia,” she says.

6. Name: Coriolanus

Description: Blood-thirsty army general, disastrous politician

Supporting quote: “Despising, for you, the city, thus I turn my back: There is a world elsewhere.”

Coriolanus is a classic case of how brilliance in one field, soldiering, doesn’t necessarily translate to another, politics. “Many productions emphasise Coriolanus’s inability to understand the politics of the real world and the necessity of custom even when you think it’s pointless,” says Erin Sullivan of the Shakespeare Institute in Stratford, UK.

Coriolanus has an extreme lack of social aptitude, and a lack of empathy: he is “a kind of nothing”. It could be argued, too, that he has a desire for routine, a desire that is frustrated when he is exiled. “They are trying to thrust him out into the crowd, they want him to make nice and he just doesn’t want to do it,” says Karim-Cooper. “That’s often attributed to his pride and sense of social superiority, but perhaps you could read it as a slightly autistic trait.”

But maybe that illustrates how we bring our own cultural and scientific baggage to the Bard. No doubt in 100 years there will be different interpretations again. Perhaps that, more than anything, shows the richness of Shakespeare’s plays.

Read more:Shakespeare: Poet, playwright, scientist?

Topics: Books and art / Epilepsy / Mental health / theatre