ҹ1000

Imagine storing all the world’s archives in a box of seeds

As our appetite for data soars, Karin Ljubic Fister is pioneering a surprising storage facility with potential to grow

Imagine storing all the world's archives in a box of seeds

You put data into plants. Why?
I was annoyed about the amount of disc space on my computer. I started wondering, what if I could store data in DNA? It’s such an immense reservoir of potential storage – 1 gram of it could store over 450 x 1018 bytes. All of the archives in the world could be stored in one box of seeds.

What was your first challenge?
Together with colleagues, we inserted a simple computer program called “Hello World” into a tobacco plant’s DNA.

How do you put computer code into DNA?
First you need a coding system. A computer program is basically a sequence of 0s and 1s, so we transformed this into the four DNA “letters” – A, G, C and T – by turning 00 into A, 10 into C, 01 into G and 11 into T. Then we synthesised the resulting DNA sequence. We transferred this artificial DNA into a bacterium and infected the leaf of a tobacco plant with it. The bacterium transfers this artificial DNA into the plant.

What happens to the data once placed inside the plant?
We took a cutting of the infected leaf, planted it, and grew a full tobacco plant from it. This is essentially cloning, so all the leaves of this new plant, and its seeds, contained the “Hello World” program encoded in their DNA.

How do you retrieve the data?
It’s not hard. You extract the plant’s DNA and sequence it using standard methods. We reconstructed the program from the resulting tobacco seedlings with complete accuracy: the message “Hello World” popped up on our computer screen.

This sort of data extraction means the destruction of some leaf material, but handheld technology is already in development that will one day enable us to read a leaf’s DNA directly, with virtually no damage.

So one day we’ll be able to browse Wikipedia from a plant?
Absolutely, with the appropriate interface – though in that scenario you would not be able to edit any entries, because data stored in DNA is read-only. That’s why it would ultimately be better suited to archiving.

How long can data stored in seeds last?
Inside the global seed vault they can be frozen and last for millennia – there’s no limit. They even have their germination ability preserved.

What future do you see for this technology?
Imagine walking through a park that is actually a library, every plant, flower and shrub full of archived information. You sit down on a bench, touch your handheld DNA reader to a leaf and listen to the Rolling Stones directly from it, or choose a novel or watch a documentary amid the greenery.

A simple tree could provide all the educational data a child anywhere in the world could need. That was my inspiration.

Profile

is a doctor at the University Medical Centre Maribor, Slovenia, and also works in computer science and genetics. She presented her work on at the in Berlin, Germany

Topics: DNA