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gene

Light micrograph section through the skin of a patient with epidermolysis bullosa (EB) showing cleavage of part of the epidermis. EB is a rare genetic disease of the connective tissues in the skin and mucosal membranes. In this condition, no collagen forms between the skin layers (the dermis and epidermis). This allows them to move across each other at the slightest pressure, resulting in blisters and painful sores. Hematoxylin and eosin stain. Magnification: x550 when printed at 10 centimetres wide.

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First ever gene therapy gel corrects rare genetic skin condition

People with recessive dystrophic epidermolysis bullosa, a genetic condition that causes widespread skin blistering, have been successfully treated by inserting new collagen genes into their skin

News

Illustration of CAR (chimeric antigen receptor) T cell immunotherapy, a process that is being developed to treat cancer. T cells (one at centre), part of the body's immune system, are taken from the patient and have their DNA (deoxyribonucleic acid) modified by viruses (spiky spheres) so that they produce chimeric antigen receptor (CAR) proteins. These proteins will be specific to the patient's cancer. The modified T cells are then multiplied in the laboratory before being reintroduced to the patient.

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Pioneering leukaemia therapy still working well after 11 years

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Blood samples

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Privacy of hundreds of thousands of genetic volunteers may be at risk

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transgenic plants

Life

Tea and banana plants have been genetically modified by bacteria

News

Your genes help determine how much sleep you need

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DNA mutation lets some people live healthily on only 4 hours' sleep

News

embryo

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2019 Preview: DNA testing will lead to a decline in genetic disorders

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DNA model

Life

Gene editing is so easy to do that we couldn’t stop it if we wanted to

Leader

A picture of a brain scan

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Gene therapy eases Parkinson’s symptoms by rewiring parts of the brain

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Amyloid protein in Alzheimer's disease.

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Morphing brain DNA hints at a whole new way to treat Alzheimer's

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37 trillion pieces of you: The plan to map the entire human body

Life

37 trillion pieces of you: The plan to map the entire human body

The workings of the myriad cells that make us are a huge mystery. A vast new project is changing that – and bringing sweeping insights into how we live and die

Features

Environment

Antibiotic resistance genes are showing up in Antarctic penguins

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A whole new type of cancer therapy helps treat liver cancer

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Life

A new synthetic molecule may solve a paradox about life's origin

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Humans

Stem cells may reveal how Neanderthal DNA works in modern humans

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